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On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who're struggling with alcoholism may benefit especially from naltrexone, one of three medications licensed by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation that creates them likely to benefit from naltrexone, weighed against about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are presently available online ( within the journal Neuropsychopharmacology and you will be published in an upcoming print edition from the journal.

Using two separate drugs to lose weight naturally can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you ought to err assisting caution and permit the FDA do its job and demand some investigation be done so your public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on their own medications.

Researchers discovered that participants using this drug for a year, dropped excess weight within one month and have kept the extra weight off through the 56 weeks in the study. Contrave is often a combination of the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which are made up of many active ingredient, which can make them more potent and safer.

Combo-pilling could be the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that by right now there aren't long term prescription diet pills that have been licensed by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise blood pressure levels and pulse rate, and mustn't be used in those with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not be used in patients with uncontrolled high blood pressure level, and also by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients having a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.


The most common negative effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.